切换至 "中华医学电子期刊资源库"

中华诊断学电子杂志 ›› 2020, Vol. 08 ›› Issue (04) : 217 -222. doi: 10.3877/cma.j.issn.2095-655X.2020.04.001

所属专题: 文献 指南共识

专题笔谈

癔球症多学科诊治中国专家共识
中华医学会行为医学分会消化病学组   
  • 收稿日期:2020-05-21 出版日期:2020-11-26

Chinese experts′ consensus on multidisciplinary diagnosis and treatment of globus sensation

Chinese Society of Behavioral Medicine   

  • Received:2020-05-21 Published:2020-11-26
  • About author:
    Corresponding author: Jia Lin, Email:
引用本文:

中华医学会行为医学分会消化病学组. 癔球症多学科诊治中国专家共识[J/OL]. 中华诊断学电子杂志, 2020, 08(04): 217-222.

Chinese Society of Behavioral Medicine. Chinese experts′ consensus on multidisciplinary diagnosis and treatment of globus sensation[J/OL]. Chinese Journal of Diagnostics(Electronic Edition), 2020, 08(04): 217-222.

癔球症发病率高,多伴发焦虑、抑郁和睡眠障碍,是临床常见的心身疾病,其诊治需要多学科参与。主要治疗方法包括抗焦虑抑郁治疗、认知行为治疗、中医中药等,但迄今国内外尚无公认的癔球症多学科诊治共识和诊治流程。本共识基于社区流行病学调查和临床注册研究,在癔球症的多学科间达成诊治共识,对临床医生开展癔球症的临床诊治和科研工作有积极的指导意义。

Globus sensation has a high incidence, accompanied by anxiety, depression and sleep disturbance, which is a commonly encountered psychosomatic disorder in clinic. Its diagnosis and treatment need multidisciplinary participation. The main treatments include anti-anxiety and anti-depression therapy, cognitive behavioral therapy, Chinese medicine, and so on. But so far, there is no recognized multidisciplinary consensus on diagnosis and treatment of globus sensation at home and abroad. This consensus is based on community epidemiological surveys and clinical registration studies, which is a positive guidance for clinicians in the diagnosis and treatment of globus sensation.

图1 癔球症多学科诊治流程图
[1]
Drossman DA.Functional fastrointestinal disorders:history,pathophysiology,clinical features and Rome IV[J].Gastroenterology,2016,150(6): 1262-1279.
[2]
Harar RP, Kumar S, Saeed MA, et al. Management of globus pharyngeus:review of 699 cases[J].J Laryngol Otol,2004,118(7): 522-527.
[3]
Thompson WG, Heaton KW.Heartburn and globus in apparently healthy people[J].Can Med Assoc J,1982,126(1): 46-48.
[4]
Moloy PJ, Charter R.The globus symptom.Incidence,therapeutic response,and age and sex relationships[J].Arch Otolaryngol,1982,108(11): 740-744.
[5]
Rasmussen ER, Schnack DT, Ravn AT.A prospective cohort study of 122 adult patients presenting to an otolaryngologist's office with globus pharyngeus[J].Clin Otolaryngol,2018,43(3): 854-860.
[6]
赵寒冰,蔡厚达,贾林,等.癔球症患者的临床发病学-精神心理特征:附559例病例分析[J].现代消化及介入诊疗,2018,23(3): 293-296.
[7]
唐见,贾林,蔡厚达,等.广州地区人群癔球症的发病学特征及域乡差异[J].中华行为医学与脑科学杂志,2016,25(6): 537-541.
[8]
Tang B, Cai HD, Xie HL,et al.Epidemiology of globus symptoms and associated psychological factors in China[J].J Dig Dis,2016,17(5): 319-324.
[9]
Tawil J, Fass R.Globus:current concepts and dilemmas[J].J Clin Gastroenterol,2018,52(10): 845-852.
[10]
Deary IJ, Wilson JA, Kelly SW.Globus pharyngis,personality,and psychological distress in the general population[J].Psychosomatics,1995,36(6): 570-577.
[11]
Harris MB, Deary IJ, Wilson JA. Life events and difficulties in relation to the onset of globus pharyngis[J].J Psychosom Res,1996,40(6): 603-615.
[12]
Tang B, Jia L, Liu J, et al. Clinical-psychological characteristics of refractory globus patients in China[J].Dig Liver Dis,2016,48(4): 381-384.
[13]
Corso MJ, Pursnani KG, Mohiuddin MA,et al.Globus sensation is associated with hypertensive upper esophageal sphincter but not with gastroesophageal reflux[J].Dig Dis Sci,1998,43(7): 1513-1517.
[14]
Peng L, Patel A, Kushnir V,et al.Assessment of upper esophageal sphincter function on high-resolution manometry:identification of predictors of globus symptoms[J].J Clin Gastroenterol,2015,49(2): 95-100.
[15]
Halum SL, Butler SG, Koufman JA,et al.Treatment of globus by upper esophageal sphincter injection with botulinum A toxin[J].Ear Nose Throat J,2005,84(2): 74.
[16]
Cook IJ, Dent J, Collins SM.Upper esophageal sphincter tone and reactivity to stress in patients with a history of globus sensation[J].Dig Dis Sci,1989,34(5): 672-676.
[17]
Nevalainen P, Walamies M, Kruuna O, et al. Supragastric belch may be related to globus symptom—a prospective clinical study[J].Neurogastroenterol Motil,2016,28(5): 680-686.
[18]
陈冬云,贾林.癔球症患者食管上括约肌压力分型及其严重程度的影响因素[J/CD].中华诊断学电子杂志,2016,4(3): 153-156.
[19]
Zhou W, Jia L, Chen D,et al.The effects of paroxetine and amitriptyline on the upper esophageal sphincter (UES) pressure and its natural history in globus pharyngeus[J].Dig Liver Dis,2017,49(7): 757-763.
[20]
Chen CL, Szczesniak MM, Cook IJ. Evidence for oesophageal visceral hypersensitivity and aberrant symptom referral in patients with globus[J].Neurogastroenterol Motil,2009,21(11): 1142-1196.
[21]
Kiebles JL, Kwiatek MA, Pandolfino JE, et al. Do patients with globus sensation respond to hypnotically assisted relaxation therapy? a case series report[J].Dis Esophagus,2010,23(7): 545-553.
[22]
Khalil HS, Bridger MW, Hilton-Pierce M,et al.The use of speech therapy in the treatment of globus pharyngeus patients.A randomised controlled trial[J].Rev Laryngol Otol Rhinol (Bord),2003,124(3): 187-190.
[23]
Deary IJ, Wilson JA.Problems in treating globus pharyngis[J].Clin Otolaryngol Allied Sci,1994,19(1): 55-60.
[24]
You L.Effect of low-dose amitriptyline on globus pharyngeus and its side effects[J].World J Gastroenterol,2013,19(42): 7455-7460.
[25]
Chen DY, Jia L, Gu X,et al.Comparison of paroxetine and amitriptyline in the treatment of refractory globus pharyngeus[J].Dig Liver Dis,2016,48(9): 1012-1017.
[26]
游乐卿,刘静,贾林.小剂量阿米替林治疗癔球症的综合疗效、副反应及其耗费[J].国际医药卫生导报,2013,19(20): 3104-3108.
[27]
Morgan V, Pickens D, Gautam S,et al.Amitriptyline reduces rectal pain related activation of the anterior cingulate cortex in patients with irritable bowel syndrome[J].Gut,2005,54(5): 601-607.
[28]
Huang W, Jiang SM, Jia L,et al.Effect of amitriptyline on gastrointestinal function and brain-gut peptides:a double-blind trial[J].World J Gastroenterol,2013,19(26): 4214-4220.
[29]
Rahimi R, Nikfar S, Rezaie A,et al.Efficacy of tricyclic antidepressants in irritable bowel syndrome:a meta-analysis[J].World J Gastroenterol,2009,15(13): 1548-1553.
[30]
江舒曼,贾林,李伟冬,等.半夏厚朴清心汤联合经皮穴位电刺激治疗癔球症的临床疗效[J].广东医学,2018,39(20): 3119-3122.
[31]
Zhou W, Deng Q, Jia L, et al. Acute effect of transcutaneous electroacupuncture on globus pharyngeus:a randomized,single-blind,crossover trial[J].Front Med (Lausanne),2020(7): 179.
[32]
何梓健,贾林,邓祺,等.癔球症患者临床精神心理学特征及少商穴经皮电刺激治疗的疗效评价[J/CD].中华诊断学电子杂志,2020,8(2): 130-134.
[33]
Timon C, O′Dwyer T, Cagney D,et al.Globus pharyngeus:long-term follow-up and prognostic factors[J].Ann Otol Rhinol Laryngol,1991,100(5 Pt 1): 351-354.
[1] 王亚红, 蔡胜, 葛志通, 杨筱, 李建初. 颅骨骨膜窦的超声表现一例[J/OL]. 中华医学超声杂志(电子版), 2024, 21(11): 1089-1091.
[2] 史学兵, 谢迎东, 谢霓, 徐超丽, 杨斌, 孙帼. 声辐射力弹性成像对不可切除肝细胞癌门静脉癌栓患者放射治疗效果的评价[J/OL]. 中华医学超声杂志(电子版), 2024, 21(08): 778-784.
[3] 唐金侨, 叶宇佳, 王港, 赵彬, 马艳宁. 医学影像学检查方法在颞下颌关节紊乱病中临床应用研究进展[J/OL]. 中华口腔医学研究杂志(电子版), 2024, 18(06): 406-411.
[4] 李华志, 曹广, 刘殿刚, 张雅静. 不同入路下行肝切除术治疗原发性肝细胞癌的临床对比[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 52-55.
[5] 陈浩, 王萌. 胃印戒细胞癌的临床病理特征及治疗选择的研究进展[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 108-111.
[6] 刘柏隆, 周祥福. 压力性尿失禁阶梯治疗的项目介绍[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2025, 19(01): 125-125.
[7] 刘柏隆. 女性压力性尿失禁阶梯治疗之手术治疗方案选择[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2025, 19(01): 126-126.
[8] 袁园园, 岳乐淇, 张华兴, 武艳, 李全海. 间充质干细胞在呼吸系统疾病模型中肺组织分布及治疗机制的研究进展[J/OL]. 中华细胞与干细胞杂志(电子版), 2024, 14(06): 374-381.
[9] 国文凯, 纪鹏程, 毕靖茹, 谢院生. IgA 肾病的十种治疗措施[J/OL]. 中华肾病研究电子杂志, 2024, 13(06): 327-333.
[10] 李浩, 陈棋帅, 费发珠, 张宁伟, 李元东, 王硕晨, 任宾. 慢性肝病肝纤维化无创诊断的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(09): 863-867.
[11] 谭瑞义. 小细胞骨肉瘤诊断及治疗研究现状与进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(08): 781-784.
[12] 王誉英, 刘世伟, 王睿, 曾娅玲, 涂禧慧, 张蒲蓉. 老年乳腺癌新辅助治疗病理完全缓解的预测因素分析[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 641-646.
[13] 王子阳, 王宏宾, 刘晓旌. 血清标志物对甲胎蛋白阴性肝细胞癌诊断的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 677-681.
[14] 陈慧, 邹祖鹏, 周田田, 张艺丹, 张海萍. 皮肤镜对头皮红斑性皮肤病辅助鉴别诊断的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 692-698.
[15] 崔军威, 蔡华丽, 胡艺冰, 胡慧. 亚甲蓝联合金属定位夹及定位钩针标记在乳腺癌辅助化疗后评估腋窝转移淋巴结的临床应用价值探究[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 625-632.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?