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中华诊断学电子杂志 ›› 2022, Vol. 10 ›› Issue (02) : 88 -93. doi: 10.3877/cma.j.issn.2095-655X.2022.02.004

心血管疾病诊治

酷似扩张型心肌病的急性心肌梗死诊断特征并文献复习
左汉恒1, 李银平1,(), 张程征1, 朱文雅2   
  1. 1. 272029 济宁医学院附属医院心内监护室
    2. 272013 济宁医学院临床医学院
  • 收稿日期:2021-03-16 出版日期:2022-04-26
  • 通信作者: 李银平
  • 基金资助:
    济宁医学院教师科研扶持基金(JYFC2019FKJ243)

Diagnostic characteristics of acute myocardial infarction resembling dilated cardiomyopathy and literature review

Hanheng Zuo1, Yinping Li1,(), Chengzheng Zhang1, Wenya Zhu2   

  1. 1. Cardiac Care Unit, Affiliated Hospital of Jining Medical University, Jining 272029, China
    2. College of Clinical Medicine, Jining Medical University, Jining 272013, China
  • Received:2021-03-16 Published:2022-04-26
  • Corresponding author: Yinping Li
引用本文:

左汉恒, 李银平, 张程征, 朱文雅. 酷似扩张型心肌病的急性心肌梗死诊断特征并文献复习[J]. 中华诊断学电子杂志, 2022, 10(02): 88-93.

Hanheng Zuo, Yinping Li, Chengzheng Zhang, Wenya Zhu. Diagnostic characteristics of acute myocardial infarction resembling dilated cardiomyopathy and literature review[J]. Chinese Journal of Diagnostics(Electronic Edition), 2022, 10(02): 88-93.

目的

探讨以心脏扩大为首发表现的急性心肌梗死的临床特点及误诊原因。

方法

回顾性分析2020年7月30日济宁医学院附属医院心内科监护室收治的1例急性心肌梗死患者的临床资料,并进行文献复习。

结果

患者41岁,男性,入院前10 d受凉后出现咳嗽,咳少量白痰,胸闷逐渐加重,活动耐力降低。心脏超声检查示左心、右房增大,左室整体功能减低,左室射血分数(LVEF)43%,诊断为扩张型心肌病,治疗3 d后患者仍感胸闷不适。入院后复查心脏超声,LVEF降至22%;行心脏磁共振成像检查符合急性心肌梗死磁共振表现;行冠状动脉造影检查发现前降支发出第一对角支后狭窄95%,第一对角支开口近段狭窄80%,于前降支狭窄处植入药物洗脱支架一枚。随访患者心脏超声,心功能恢复良好,出院后8个月LVEF升至56%。

结论

心脏磁共振成像检查对不典型急性心肌梗死诊断具有重要意义;血运重建及充分药物治疗可以逆转急性心肌梗死心室重构。

Objective

To explore the clinical characteristics and misdiagnosis reasons of acute myocardial infarction with cardiac enlargement as the first manifestation.

Methods

The clinical data of a patient with acute myocardial infarction admitted to the Cardiac Care Unit of Affiliated Hospital of Jining Medical University on July 30, 2020 was retrospectively analyzed, and relative literatures were reviewed.

Results

The 41-year-old patient developed a cough and a small amount of white phlegm for 10 days before admitted to the hospital, with gradually increasing chest tightness, and decreasing activity endurance. Echocardiography showed left ventricle and right atrium was enlarged, left ventricle contraction was markedly impaired, and left ventricular ejection fraction (LVEF) was 43%. He was diagnosed with dilated cardiomyopathy, and still felt chest tightness and discomfort after 3 days of treatment. After admission, echocardiography showed that LVEF decreased to 22% and the manifestations of cardiac MRI were consistent with the changes of acute myocardial infarction. Coronary angiography showed that the stenosis in LAD after D1 was 95%, the proximal part of D1 stenosis was 80%, and a drug-eluting stent was implanted at the stenosis of LAD. Following discharge, follow-up echocardiography revealed good heart function recovery, with LVEF increasing to 56% 8 months later.

Conclusions

Cardiac MRI is of great significance in the diagnosis of atypical acute myocardial infarction. Revascularization and adequate medical treatment can reverse ventricular remodeling in acute myocardial infarction.

图1 急性心肌梗死患者入院及随访时心电图图像注:a图为患者入院时心电图图像,示窦性心律,心率105次/min,P-R间期:172 ms,QRS:118 ms,QT/QTc:348/460 ms,RV5+SV1=3.03 mV,V1、V2导联呈QS,V3导联呈SqRs,诊断提示窦性心动过速,左室高电压,ST-T改变,异常Q/q波(V1~V3);b图为患者出院后3个月复查心电图图像,示窦性心律,心率93次/min,P-R间期:139 ms,QRS:158 ms,QT/QTc:408/508 ms,RV5+SV1=2.51 mV,V1呈R,其上可见切迹,V5呈RS,诊断提示窦性心律,完全性右束支传导阻滞。纸速:25 mm/s,灵敏度:10 mm/mV
图2 急性心肌梗死患者心脏磁共振检查图像注:a图为心脏T2加权像,示左心室前壁、前间壁信号增高;b图示心肌静息灌注加权成像,示左心室壁未见明显异常灌注及缺损;c图示心肌延迟强化成像,示左心室前壁、前间隔壁心内膜下见线样明显钆延迟强化(箭头所示)
图3 急性心肌梗死患者冠状动脉造影及经皮冠状动脉介入治疗图像注:a图冠状动脉造影左主干未见异常,前降支发出第一对角支后狭窄95%,第一对角支开口近段狭窄80%;b图回旋支未见异常;c图右冠状动脉粗大,中段狭窄20%~30%;d图示3.5 mm×15.0 mm球囊预扩张前降支病变处后植入一枚3.0×16.0 mm依维莫司药物洗脱支架;e图示3.7 mm×9.0 mm球囊进入前降支支架内,2.0×15.0 mm球囊进入第一对角支开口近段病变处行对吻扩张;f图示支架贴壁良好,未见残余狭窄(箭头所示)
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