| [1] |
Flemming HC, Wingender J. The biofilm matrix[J]. Nat Rev Microbiol， 2010， 8(9)：623-633.DOI： 10.1038/nrmicro2415.
|
| [2] |
Aliramezani A， Douraghi M， Hajihasani A，et al.Clonal relatedness and biofilm formation of OXA-23-producing carbapenem resistant Acinetobacter baumannii isolates from hospital environment[J]. Microb Pathog， 2016(99)：204-208.DOI： 10.1016/j.micpath.2016.08.034.
|
| [3] |
Reddy VS, Shlykov MA, Castillo R, et al. The major facilitator superfamily (MFS) revisited[J]. FEBS J， 2012， 279(11)：2022-2035.DOI： 10.1111/j.1742-4658.2012.08588.x.
|
| [4] |
Pasqua M， Grossi M， Zennaro A，et al.The varied role of efflux pumps of the MFS family in the interplay of Bacteria with animal and plant cells[J]. Microorganisms， 2019， 7(9)：285.DOI： 10.3390/microorganisms7090285.
|
| [5] |
Ernst M， Robertson JL.The role of the membrane in transporter folding and activity[J]. J Mol Biol， 2021， 433(16)：167103.DOI： 10.1016/j.jmb.2021.167103.
|
| [6] |
Jeckelmann JM， Erni B．Carbohydrate transport by group translocation：the bacterial phosphoenolpyruvate：sugar phosphotransferase system[J]. Subcell Biochem， 2019(92)：223-274.DOI： 10.1007/978-3-030-18768-2_8.
|
| [7] |
|
| [8] |
Marger MD, Saier MH Jr. A major superfamily of transmembrane facilitators that catalyse uniport，symport and antiport[J]. Trends Biochem Sci， 1993， 18(1)：13-20.DOI： 10.1016/0968-0004(93)90081-w.
|
| [9] |
Drew D， North RA， Nagarathinam K，et al.Structures and general transport mechanisms by the major facilitator superfamily(MFS)[J]. Chem Rev， 2021， 121(9)：5289-5335.DOI： 10.1021/acs.chemrev.0c00983.
|
| [10] |
|
| [11] |
Madej MG， Dang S， Yan N，et al.Evolutionary mix-and-match with MFS transporters[J]. Proc Natl Acad Sci U S A， 2013， 110(15)：5870-5874.DOI： 10.1073/pnas.1303538110.
|
| [12] |
Boudker O， Verdon G．Structural perspectives on secondary active transporters[J]. Trends Pharmacol Sci， 2010， 31(9)：418-426.DOI： 10.1016/j.tips.2010.06.004.
|
| [13] |
|
| [14] |
Abramson J， Smirnova I， Kasho V，et al.Structure and mechanism of the lactose permease of Escherichia coli[J]. Science， 2003， 301(5633)：610-615.DOI： 10.1126/science.1088196.
|
| [15] |
Huang Y， Lemieux MJ， Song J，et al.Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli[J]. Science， 2003， 301(5633)：616-620.DOI： 10.1126/science.1087619.
|
| [16] |
Sun L， Zeng X， Yan C，et al.Crystal structure of a bacterial homologue of glucose transporters GLUT1-4[J]. Nature， 2012， 490(7420)：361-366.DOI： 10.1038/nature11524.
|
| [17] |
Deng D， Xu C， Sun P，et al.Crystal structure of the human glucose transporter GLUT1[J]. Nature， 2014， 510(7503)：121-125.DOI： 10.1038/nature13306.
|
| [18] |
|
| [19] |
Smirnova IN， Kasho V， Kaback HR.Protonation and sugar binding to LacY[J]. Proc Natl Acad Sci U S A， 2008， 105(26)：8896-8901.DOI： 10.1073/pnas.0803577105.
|
| [20] |
Garcia íR, de Oliveira Garcia FA, Pereira PS, et al. Microbial resistance：the role of efflux pump superfamilies and their respective substrates[J]. Life Sci， 2022(295)：120391.DOI： 10.1016/j.lfs.2022.120391.
|
| [21] |
May T， Ito A， Okabe S．Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes[J]. Antimicrob Agents Chemother， 2009， 53(11)：4628-4639.DOI： 10.1128/AAC.00454-09.
|
| [22] |
Bay DC， Stremick CA， Slipski CJ，et al.Secondary multidrug efflux pump mutants alter Escherichia coli biofilm growth in the presence of cationic antimicrobial compounds[J]. Res Microbiol， 2017， 168(3)：208-221.DOI： 10.1016/j.resmic.2016.11.003.
|
| [23] |
Matsumura K， Furukawa S， Ogihara H，et al.Roles of multidrug efflux pumps on the biofilm formation of Escherichia coli K-12[J]. Biocontrol Sci， 2011， 16(2)：69-72.DOI： 10.4265/bio.16.69.
|
| [24] |
Sun J， Deng Z， Yan A．Bacterial multidrug efflux pumps：mechanisms，physiology and pharmacological exploitations[J]. Biochem Biophys Res Commun， 2014， 453(2)：254-267.DOI： 10.1016/j.bbrc.2014.05.090.
|
| [25] |
Junker LM， Peters JE， Hay AG.Global analysis of candidate genes important for fitness in a competitive biofilm using DNA-array-based transposon mapping[J]. Microbiology (Reading)， 2006， 152(Pt 8)：2233-2245.DOI： 10.1099/mic.0.28767-0.
|
| [26] |
Kvist M， Hancock V， Klemm P．Inactivation of efflux pumps abolishes bacterial biofilm formation[J]. Appl Environ Microbiol， 2008， 74(23)：7376-7382.DOI： 10.1128/AEM.01310-08.
|
| [27] |
Koita K， Rao CV.Identification and analysis of the putative pentose sugar efflux transporters in Escherichia coli[J]. PLoS One， 2012， 7(8)：e43700.DOI： 10.1371/journal.pone.0043700.
|
| [28] |
Beloin C， Valle J， Latour-Lambert P，et al.Global impact of mature biofilm lifestyle on Escherichia coli K-12 gene expression[J]. Mol Microbiol， 2004， 51(3)：659-674.DOI： 10.1046/j.1365-2958.2003.03865.x.
|
| [29] |
Podolsky T， Fong ST， Lee BT.Direct selection of tetracycline-sensitive Escherichia coli cells using nickel salts[J]. Plasmid， 1996， 36(2)：112-115.DOI： 10.1006/plas.1996.0038.
|
| [30] |
Tu Quoc PH， Genevaux P， Pajunen M，et al.Isolation and characterization of biofilm formation-defective mutants of Staphylococcus aureus[J]. Infect Immun， 2007， 75(3)：1079-1088.DOI： 10.1128/IAI.01143-06.
|
| [31] |
He X， Ahn J．Differential gene expression in planktonic and biofilm cells of multiple antibiotic-resistant Salmonella Typhimurium and Staphylococcus aureus[J]. FEMS Microbiol Lett， 2011， 325(2)：180-188.DOI： 10.1111/j.1574-6968.2011.02429.x.
|
| [32] |
Resch A， Rosenstein R， Nerz C，et al.Differential gene expression profiling of Staphylococcus aureus cultivated under biofilm and planktonic conditions[J]. Appl Environ Microbiol， 2005， 71(5)：2663-2676.DOI： 10.1128/AEM.71.5.2663-2676.2005.
|
| [33] |
Sharma A， Sharma R， Bhattacharyya T，et al.Fosfomycin resistance in Acinetobacter baumannii is mediated by efflux through a major facilitator superfamily (MFS) transporter-AbaF[J]. J Antimicrob Chemother， 2017， 72(1)：68-74.DOI： 10.1093/jac/dkw382.
|
| [34] |
Rumbo-Feal S， Gómez MJ， Gayoso C，et al.Whole transcriptome analysis of Acinetobacter baumannii assessed by RNA-sequencing reveals different mRNA expression profiles in biofilm compared to planktonic cells[J]. PLoS One， 2013， 8(8)：e72968.DOI： 10.1371/journal.pone.0072968.
|
| [35] |
Sahu PK， Iyer PS， Gaikwad MB，et al.An MFS transporter-like ORF from MDR Acinetobacter baumannii AIIMS 7 is associated with adherence and biofilm formation on Biotic/Abiotic surface[J]. Int J Microbiol， 2012(2012)：490647.DOI： 10.1155/2012/490647.
|
| [36] |
Baugh S， Ekanayaka AS， Piddock LJ，et al.Loss of or inhibition of all multidrug resistance efflux pumps of Salmonella enterica serovar Typhimurium results in impaired ability to form a biofilm[J]. J Antimicrob Chemother， 2012， 67(10)：2409-2417.DOI： 10.1093/jac/dks228.
|
| [37] |
Waite RD， Papakonstantinopoulou A， Littler E，et al.Transcriptome analysis of Pseudomonas aeruginosa growth：comparison of gene expression in planktonic cultures and developing and mature biofilms[J]. J Bacteriol， 2005， 187(18)：6571-6576.DOI： 10.1128/JB.187.18.6571-6576.2005.
|
| [38] |
Holling N， Lednor D， Tsang S，et al.Elucidating the genetic basis of crystalline biofilm formation in Proteus mirabilis[J]. Infect Immun， 2014， 82(4)：1616-1626.DOI： 10.1128/IAI.01652-13.
|
| [39] |
Vasicek EM， O'Neal L， Parsek MR，et al.L-Arabinose transport and metabolism in salmonella influences biofilm formation[J]. Front Cell Infect Microbiol， 2021(11)：698146.DOI： 10.3389/fcimb.2021.698146.
|
| [40] |
Alav I， Sutton JM， Rahman KM.Role of bacterial efflux pumps in biofilm formation[J]. J Antimicrob Chemother， 2018， 73(8)：2003-2020.DOI： 10.1093/jac/dky042.
|
| [41] |
Zimmermann S， Klinger-Strobel M， Bohnert JA，et al.Clinically approved drugs inhibit the staphylococcus aureus multidrug NorA efflux pump and reduce biofilm formation[J]. Front Microbiol， 2019(10)：2762.DOI： 10.3389/fmicb.2019.02762.
|
| [42] |
Mahey N， Tambat R， Verma DK，et al.Antifungal azoles as tetracycline resistance modifiers in staphylococcus aureus[J]. Appl Environ Microbiol， 2021， 87(15)：e0015521.DOI： 10.1128/AEM.00155-21.
|
| [43] |
Yun EJ， Cho Y， Han NR，et al.Increased production of colanic acid by an engineered escherichia coli strain，mediated by genetic and environmental perturbations[J]. Appl Biochem Biotechnol， 2021， 193(12)：4083-4096.DOI： 10.1007/s12010-021-03671-0.
|
| [44] |
Pisithkul T， Schroeder JW， Trujillo EA，et al.Metabolic remodeling during biofilm development of bacillus subtilis[J]. mBio， 2019， 10(3)：e00623-19.DOI： 10.1128/mBio.00623-19.
|
| [45] |
Lu H， Que Y， Wu X，et al.Metabolomics deciphered metabolic reprogramming required for biofilm formation[J]. Sci Rep， 2019， 9(1)：13160.DOI： 10.1038/s41598-019-49603-1.
|
| [46] |
Costa SS， Viveiros M， Amaral L，et al.Multidrug efflux pumps in staphylococcus aureus：an update[J]. Open Microbiol J， 2013(7)：59-71.DOI： 10.2174/1874285801307010059.
|
| [47] |
Trotonda MP， Tamber S， Memmi G，et al.MgrA represses biofilm formation in Staphylococcus aureus[J]. Infect Immun， 2008， 76(12)：5645-5654.DOI： 10.1128/IAI.00735-08.
|
| [48] |
Yang R， Lai B， Liao K，et al.Overexpression of BIT33_RS14560 enhances the biofilm formation and virulence of Acinetobacter baumannii[J]. Front Microbiol， 2022(13)：867770.DOI： 10.3389/fmicb.2022.867770.
|