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中华诊断学电子杂志 ›› 2023, Vol. 11 ›› Issue (02) : 125 -127. doi: 10.3877/cma.j.issn.2095-655X.2023.02.011

内分泌代谢性疾病诊治

硒联合不同药物治疗桥本甲状腺炎的研究进展
王正宇1, 孙琳2,()   
  1. 1. 272013 济宁医学院临床医学院
    2. 272002 济宁市第一人民医院内分泌科
  • 收稿日期:2022-01-29 出版日期:2023-05-04
  • 通信作者: 孙琳

Research progress of selenium combined with different drugs in the treatment of Hashimoto thyroiditis

Zhengyu Wang1, Lin Sun2,()   

  1. 1. College of Clinical Medicine, Jining Medical University, Jining 272013, China
    2. Department of Endocrinology, the First People′s Hospital of Jining, Jining 272002, China
  • Received:2022-01-29 Published:2023-05-04
  • Corresponding author: Lin Sun
引用本文:

王正宇, 孙琳. 硒联合不同药物治疗桥本甲状腺炎的研究进展[J/OL]. 中华诊断学电子杂志, 2023, 11(02): 125-127.

Zhengyu Wang, Lin Sun. Research progress of selenium combined with different drugs in the treatment of Hashimoto thyroiditis[J/OL]. Chinese Journal of Diagnostics(Electronic Edition), 2023, 11(02): 125-127.

硒是对人体健康必不可少的微量矿物质,在人体中以硒蛋白的形式存在,参与抗氧化、抗炎过程及活性甲状腺激素的产生。体内硒蛋白含量不足可能导致氧化应激失衡、下调机体免疫功能,从而参与桥本甲状腺炎(HT)疾病的发生发展,而补充硒可能有助于HT的预防和治疗。目前国内外已经开始重视硒缺乏与HT的相关性研究,对其预防、治疗也在进一步地探索。笔者主要对硒联合其他药物治疗HT的研究进展进行综述。

Selenium is a trace mineral that is essential for maintaining human health. Selenium is present in the body as selenoproteins, which are involved in antioxidant, anti-inflammatory process, and the production of active thyroid hormone synthesis. The imbalance of oxidative stress and the downregulation of immune function that results from a lack of selenoproteins in the body may contribute to the occurrence and progression of Hashimoto thyroiditis (HT). Selenium supplementation may aid in the prevention and treatment of HT. The study of the relationship between selenium insufficiency and HT, as well as the prevention and treatment of selenium deficiency, has begun to attract domestic and international attention. This article discusses recent developments in selenium and its use in combination with other drugs for the prevention and treatment of HT.

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