[1] |
Tatemoto K, Hosoya M, Habata Y,et al.Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor[J]. Biochem Biophys Res Commun, 1998, 251(2):471-476.DOI: 10.1006/bbrc.1998.9489.PMID: 9792798.
|
[2] |
Li A, Zhao Q, Chen L, et al. Apelin/APJ system: an emerging therapeutic target for neurological diseases[J]. Mol Biol Rep, 2023, 50(2):1639-1653.DOI: 10.1007/s11033-022-08075-9.
|
[3] |
|
[4] |
|
[5] |
Scimia MC, Hurtado C, Ray S,et al.APJ acts as a dual receptor in cardiac hypertrophy[J]. Nature, 2012, 488(7411): 394-398.DOI: 10.1038/nature11263.
|
[6] |
Liu Y, Wang L, Shi H.The biological function of ELABELA and APJ signaling in the cardiovascular system and pre-eclampsia[J]. Hypertens Res, 2019, 42(7):928-934.DOI: 10.1038/s41440-018-0193-3.
|
[7] |
Rikitake Y.The apelin/APJ system in the regulation of vascular tone: friend or foe?[J]. J Biochem, 2021, 169(4):383-386.DOI: 10.1093/jb/mvaa129.
|
[8] |
Rozwadowski J, Borodzicz-Jażdżyk S, Czarzasta K,et al.A review of the roles of apelin and ELABELA peptide ligands in cardiovascular disease,including heart failure and hypertension[J]. Med Sci Monit, 2022(28):e938112.DOI: 10.12659/MSM.938112.
|
[9] |
Tian Y, Chen R, Jiang Y,et al.The protective effects and mechanisms of apelin/APJ system on ischemic stroke: a promising therapeutic target[J]. Front Neurol, 2020(11):75.DOI: 10.3389/fneur.2020.00075.
|
[10] |
Perjés Á, Skoumal R, Tenhunen O,et al.Apelin increases cardiac contractility via protein kinase Cε-and extracellular signal-regulated kinase-dependent mechanisms[J]. PLoS One, 2014, 9(4):e93473.DOI: 10.1371/journal.pone.0093473.
|
[11] |
陈柏荣,罗礼云,黄茵,等.Apelin-13在自发性高血压大鼠心肌组织的表达及其与心肌肥厚和心功能的关系[J].中国动脉硬化杂志,2016,24(4):375-380.
|
[12] |
Li C, Cheng H, Adhikari BK,et al.The role of apelin-APJ system in diabetes and obesity[J]. Front Endocrinol (Lausanne), 2022(13):820002.DOI: 10.3389/fendo.2022.820002.
|
[13] |
Gao Z, Zhong X, Tan YX, et al. Apelin-13 alleviates diabetic nephropathy by enhancing nitric oxide production and suppressing kidney tissue fibrosis[J]. Int J Mol Med, 2021, 48(3):175.DOI: 10.3892/ijmm.2021.5008.
|
[14] |
Chen H, Zheng C, Zhang X,et al.Apelin alleviates diabetes-associated endoplasmic reticulum stress in the pancreas of Akita mice[J]. Peptides, 2011, 32(8):1634-1639.DOI: 10.1016/j.peptides.2011.06.025.
|
[15] |
Jiang Y, Wang S, Liu X.Low serum apelin levels are associated with mild cognitive impairment in type 2 diabetic patients[J]. BMC Endocr Disord, 2022, 22(1):137.DOI: 10.1186/s12902-022-01051-1.
|
[16] |
|
[17] |
Tasci I, Erdem G, Ozgur G,et al.LDL-cholesterol lowering increases plasma apelin in isolated hypercholesterolemia[J]. Atherosclerosis, 2009, 204(1):222-228.DOI: 10.1016/j.atherosclerosis.2008.08.030.
|
[18] |
Yamamoto T, Habata Y, Matsumoto Y,et al.Apelin-transgenic mice exhibit a resistance against diet-induced obesity by increasing vascular mass and mitochondrial biogenesis in skeletal muscle[J]. Biochim Biophys Acta, 2011, 1810(9):853-862.DOI: 10.1016/j.bbagen.2011.05.004.
|
[19] |
Yue P, Jin H, Xu S,et al.Apelin decreases lipolysis via G(q),G(i),and AMPK-Dependent Mechanisms[J]. Endocrinology, 2011, 152(1):59-68.DOI: 10.1210/en.2010-0576.
|
[20] |
Huang J, Kang S, Park SJ,et al.Apelin protects against liver X receptor-mediated steatosis through AMPK and PPARα in human and mouse hepatocytes[J]. Cell Signal, 2017(39):84-94.DOI: 10.1016/j.cellsig.2017.08.003.
|
[21] |
Fraga-Silva RA, Seeman H, Montecucco F,et al.Apelin-13 treatment enhances the stability of atherosclerotic plaques[J]. Eur J Clin Invest, 2018, 48(3):e12891.DOI: 10.1111/eci.12891.
|
[22] |
De Mota N, Reaux-Le Goazigo A, El Messari S,et al.Apelin,a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release[J]. Proc Natl Acad Sci U S A, 2004, 101(28):10464-10469.DOI: 10.1073/pnas.0403518101.
|
[23] |
Tian Y, Wang R, Liu L,et al.The regulatory effects of the apelin/APJ system on depression:a prospective therapeutic target[J]. Neuropeptides, 2023(102):102382.DOI: 10.1016/j.npep.2023.102382.
|
[24] |
Lee DK, Jeong JH, Oh S,et al.Apelin-13 enhances arcuate POMC neuron activity via inhibiting M-current[J]. PLoS One, 2015, 10(3):e0119457.DOI: 10.1371/journal.pone.0119457.
|
[25] |
Drougard A, Duparc T, Brenachot X,et al.Hypothalamic apelin/reactive oxygen species signaling controls hepatic glucose metabolism in the onset of diabetes[J]. Antioxid Redox Signal, 2014, 20(4):557-573.DOI: 10.1089/ars.2013.5182.
|
[26] |
Drougard A, Fournel A, Marlin A,et al.Central chronic apelin infusion decreases energy expenditure and thermogenesis in mice[J]. Sci Rep, 2016(6):31849.DOI: 10.1038/srep31849.
|
[27] |
Charles CJ, Rademaker MT, Richards AM. Apelin-13 induces a biphasic haemodynamic response and hormonal activation in normal conscious sheep[J]. J Endocrinol, 2006, 189(3):701-710.DOI: 10.1677/joe.1.06804.
|
[28] |
Newson MJ, Pope GR, Roberts EM,et al.Stress-dependent and gender-specific neuroregulatory roles of the apelin receptor in the hypothalamic-pituitary-adrenal axis response to acute stress[J]. J Endocrinol, 2013, 216(1):99-109.DOI: 10.1530/JOE-12-0375.
|
[29] |
Lv SY, Chen WD, Wang YD.The apelin/APJ system in psychosis and neuropathy[J]. Front Pharmacol, 2020(11):320.DOI: 10.3389/fphar.2020.00320.
|
[30] |
Haghparast E, Esmaeili-Mahani S, Abbasnejad M,et al.Apelin-13 ameliorates cognitive impairments in 6-hydroxydopamine-induced substantia nigra lesion in rats[J]. Neuropeptides, 2018(68):28-35.DOI: 10.1016/j.npep.2018.01.001.
|
[31] |
Zhu J, Dou S, Jiang Y, et al. Apelin-13 protects dopaminergic neurons in MPTP-induced Parkinson′s disease model mice through inhibiting endoplasmic reticulum stress and promoting autophagy[J]. Brain Res, 2019(1715):203-212.DOI: 10.1016/j.brainres.2019.03.027.
|
[32] |
Gok Oguz E, Akoglu H, Ulusal Okyay G, et al. Serum apelin is associated with affective disorders in peritoneal dialysis patients[J]. Ren Fail, 2016, 38(7):1059-1066.DOI: 10.1080/0886022X.2016.1193873.
|
[33] |
Dai TT, Wang B, Xiao ZY,et al. Apelin-13 upregulates BDNF against chronic stress-induced depression-like phenotypes by ameliorating HPA axis and hippocampal glucocorticoid receptor dysfunctions[J]. Neuroscience, 2018(390):151-159.DOI: 10.1016/j.neuroscience.2018.08.018.
|
[34] |
Xiao ZY, Wang B, Fu W,et al.The hippocampus is a critical site mediating antidepressant-like activity of apelin-13 in rats[J]. Neuroscience, 2018(375):1-9.DOI: 10.1016/j.neuroscience.2018.02.001.
|
[35] |
Fan J, Guang H, Zhang H,et al.SIRT1 mediates apelin-13 in ameliorating chronic normobaric hypoxia-induced anxiety-like behavior by suppressing NF-κB pathway in mice hippocampus[J]. Neuroscience, 2018(381):22-34.DOI: 10.1016/j.neuroscience.2018.04.013.
|
[36] |
Gourdy P, Cazals L, Thalamas C, et al. Apelin administration improves insulin sensitivity in overweight men during hyperinsulinaemic-euglycaemic clamp[J]. Diabetes Obes Metab, 2018, 20(1):157-164.DOI: 10.1111/dom.13055.
|