| [1] |
Xia L， Zhang C， Lv N，et al. AdMSC-derived exosomes alleviate acute lung injury via transferring mitochondrial component to improve homeostasis of alveolar macrophages[J]． Theranostics， 2022， 12(6)：2928-2947.DOI： 10.7150/thno.69533.
|
| [2] |
|
| [3] |
Mimitou EP, Lareau CA, Chen KY, et al. Scalable, multimodal profiling of chromatin accessibility，gene expression，and protein levels in single cells[J]． Nat Biotechnol， 2021， 39(10)：1246-1258.DOI： 10.1038/s41587-021-00927-2.
|
| [4] |
Kim DH， Kim YS， Son NI，et al.Recent omics technologies and their emerging applications for personalised medicine[J]． IET Syst Biol， 2017， 11(3)：87-98.DOI： 10.1049/iet-syb.2016.0016.
|
| [5] |
Barabási AL, Gulbahce N, Loscalzo J. Network medicine: a network-based approach to human disease[J]． Nat Rev Genet， 2011， 12(1)：56-68.DOI： 10.1038/nrg2918.
|
| [6] |
Cao L， Zhang Q， Miao R，et al.Application of omics technology in the research on edible fungi[J]． Curr Res Food Sci， 2023(6)：100430.DOI： 10.1016/j.crfs.2022.100430.
|
| [7] |
Yang X, Wang J, Liu W. Molecular markers of type Ⅱ alveolar epithelial cells in acute lung injury by bioinformatics analysis[J]． Sci Rep， 2023， 13(1)：17797.DOI： 10.1038/s41598-023-45129-9.
|
| [8] |
Nakagawa H， Fujita M．Whole genome sequencing analysis for cancer genomics and precision medicine[J]． Cancer Sci， 2018， 109(3)：513-522.DOI： 10.1111/cas.13505.
|
| [9] |
Sen′kova AV， Savin IA， Brenner EV，et al.Core genes involved in the regulation of acute lung injury and their association with COVID-19 and tumor progression：a bioinformatics and experimental study[J]． PLoS One， 2021， 16(11)：e0260450.DOI： 10.1371/journal.pone.0260450.
|
| [10] |
Tanaka T， Narazaki M， Kishimoto T．IL-6 in inflammation，immunity，and disease[J]． Cold Spring Harb Perspect Biol， 2014， 6(10)：a016295.DOI： 10.1101/cshperspect.a016295.
|
| [11] |
Hirano T．IL-6 in inflammation，autoimmunity and cancer[J]． Int Immunol， 2021， 33(3)：127-148.DOI： 10.1093/intimm/dxaa078.
|
| [12] |
Wang S， Song Y， Xu F，et al.Identification and validation of ferroptosis-related genes in lipopolysaccharide-induced acute lung injury[J]． Cell Signal， 2023(108)：110698.DOI： 10.1016/j.cellsig.2023.110698.
|
| [13] |
Shi Z， Zhu X， Gao W，et al.Extracorporeal membrane oxygenation in acute respiratory distress syndrome caused by elderly tuberculous meningitis：a case report and review of the literature[J]． Front Med (Lausanne)， 2024(11)：1457413.DOI： 10.3389/fmed.2024.1457413.
|
| [14] |
Lv M， Zhu C， Zhu C，et al.Clinical values of metagenomic next-generation sequencing in patients with severe pneumonia：a systematic review and meta-analysis[J]． Front in Cell Infect Microbiol， 2023(13)：1106859.DOI： 10.3389/fcimb.2023.1106859.
|
| [15] |
Lin XT, Liang SS, Wang QH, et al. Metagenomics approach the intestinal microbiome structure and function in the anti-H1N1 of a traditional chinese medicine acid polysaccharide[J]． Microb Pathog， 2020(147)：104351.DOI： 10.1016/j.micpath.2020.104351.
|
| [16] |
Xu Y， Zhu J， Feng B，et al.Immunosuppressive effect of mesenchymal stem cells on lung and gut CD8(＋) T cells in lipopolysaccharide-induced acute lung injury in mice[J]． Cell Prolif， 2021， 54(5)：e13028.DOI： 10.1111/cpr.13028.
|
| [17] |
|
| [18] |
Raghavan V， Kraft L， Mesny F，et al.A simple guide to de novo transcriptome assembly and annotation[J]． Brief Bioinform， 2022， 23(2)：bbab563.DOI： 10.1093/bib/bbab563.
|
| [19] |
Lu J， Sheng Y， Qian W，et al.scRNA-seq data analysis method to improve analysis performance[J]． IET Nanobiotechnol， 2023， 17(3)：246-256.DOI： 10.1049/nbt2.12115.
|
| [20] |
Shen Y, Gong L, Xu F, et al. Insight into the lncRNA-mRNA co-expression profile and ceRNA network in lipopolysaccharide-induced acute lung injury[J]． Curr Issues Mol Biol， 2023， 45(7)：6170-6189.DOI： 10.3390/cimb45070389.
|
| [21] |
Song M， Zhang X， Gao Y，et al.RNA sequencing reveals the emerging role of bronchoalveolar lavage fluid exosome lncRNAs in acute lung injury[J]． PeerJ， 2022(10)：e13159.DOI： 10.7717/peerj.13159.
|
| [22] |
Cui E， Zhang L， Pan X，et al.RNA-sequencing approach for exploring the therapeutic effect of umbilical cord mesenchymal stem/stromal cells on lipopolysaccharide-induced acute lung injury[J]． Front in Immunol， 2022(13)：1021102.DOI： 10.3389/fimmu.2022.1021102.
|
| [23] |
Paris AJ， Hayer KE， Oved JH，et al.STAT3-BDNF-TrkB signalling promotes alveolar epithelial regeneration after lung injury[J]． Nat Cell Biol， 2020， 22(10)：1197-1210.DOI： 10.1038/s41556-020-0569-x.
|
| [24] |
Cao C, Memete O, Shao Y, et al. Single-cell RNA-sequencing reveals epithelial cell signature of multiple subtypes in chemically induced acute lung injury[J]． Int J Mol Sci， 2022， 24(1)：277.DOI： 10.3390/ijms24010277.
|
| [25] |
|
| [26] |
Makhmut A， Qin D， Fritzsche S，et al.A framework for ultra-low-input spatial tissue proteomics[J]． Cell Syst， 2023， 14(11)：1002-1014.e5.DOI： 10.1016/j.cels.2023.10.003.
|
| [27] |
Yang B， Gao Z， Li Q S，et al.Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in mice[J]． Inflamm Res， 2022， 71(10-11)：1327-1345.DOI： 10.1007/s00011-022-01623-w.
|
| [28] |
Zheng Q， Zhang Y， Zhao Z，et al.Isorhynchophylline ameliorates paraquat-induced acute kidney injury by attenuating oxidative stress and mitochondrial damage via regulating toll-interacting expression[J]． Toxicology and Applied Pharmacology， 2021(420)：115521.DOI： 10.1016/j.tapa.2021.1115521.
|
| [29] |
Li Y， Xing J， Qin L，et al.Mechanism of isorhynchophylline in lipopolysaccharide-induced acute lung injury based on proteomic technology[J]． Front.Pharmacol， 2024(15)：1397498.DOI： 10.3389/fphar.2024.1397498.
|
| [30] |
Shaikh SB， Najar MA， Prasad T，et al.Comparative protein profiling reveals the inhibitory role of curcumin on IL-17A mediated minichromosome maintenance (MCM) proteins as novel putative markers for acute lung injury in vivo[J]． Biomed Pharmacother， 2021(141)：111715.DOI： 10.1016/j.biopha.2021.111715.
|
| [31] |
Hoseinnia S， Ghane M， Norouzi J，et al.Mesenchymal stem cell and endothelial progenitor cells coinjection improves LPS-induced lung injury via Tie2 activation and downregulation of the TLR4/MyD88 pathway[J]． J Cell Biochem， 2021， 122(12)：1791-1804.DOI： 10.1002/jcb.30133.
|
| [32] |
Wang H, Luo J, Li A, et al. Proteomic and phosphorylated proteomic landscape of injured lung in juvenile septic rats with therapeutic application of umbilical cord mesenchymal stem cells[J]． Front in Immunol， 2022(13)：1034821.DOI： 10.3389/fimmu.2022.1034821.
|
| [33] |
Mao Y， Chen Y， Li Y，et al.Deep spatial proteomics reveals region-specific features of severe COVID-19-related pulmonary injury[J]． Cell Rep， 2024， 43(2)：113689.DOI： 10.1016/j.celrep.2024.113689.
|
| [34] |
Bardanzellu F， Fanos V．How could metabolomics change pediatric health？[J]． Ital J Pediatr， 2020， 46(1)：37.DOI： 10.1186/s13052-020-0807-7.
|
| [35] |
Hu L, Liu J, Zhang W, et al. Functional metabolomics decipher biochemical functions and associated mechanisms underlie small-molecule metabolism[J]． Mass Spectrom Rev， 2020， 39(5-6)：417-433.DOI： 10.1002/mas.21611.
|
| [36] |
|
| [37] |
|
| [38] |
Gao L， Yuan H， Xu E，et al.Toxicology of paraquat and pharmacology of the protective effect of 5-hydroxy-1-methylhydantoin on lung injury caused by paraquat based on metabolomics[J]． Sci Rep， 2020， 10(1)：1790.DOI： 10.1038/s41598-020-58599-y.
|
| [39] |
Chetty A， Blekhman R．Multi-omic approaches for host-microbiome data integration[J]． Gut Microbes， 2024， 16(1)：2297860.DOI： 10.1080/19490976.2023.2297860.
|
| [40] |
El-Sayed A, Aleya L, Kamel M. Microbiota′s role in health and diseases[J]． Environ Sci and Pollut Res Int， 2021， 28(28)：36967-36983.DOI： 10.1007/s11356-021-14593-z.
|
| [41] |
Zheng L， Liu C， Wang H，et al.Intact lung tissue and bronchoalveolar lavage fluid are both suitable for the evaluation of murine lung microbiome in acute lung injury[J]． Microbiome， 2024， 12(1)：56.DOI： 10.1186/s40168-024-01772-6.
|
| [42] |
Jiang L, Cun Y, Wang Q, et al. Predicting acute lung injury in infants with congenital heart disease after cardiopulmonary bypass by gut microbiota[J]． Front Immunol， 2024(15)：1362040.DOI： 10.3389/fimmu.2024.1362040.
|
| [43] |
Wu X， Qin L， Song M，et al.Metagenomics combined with untargeted metabolomics to study the mechanism of miRNA-150-5p on SiO(2)-induced acute lung injury[J]． J Pharm Biomed Anal， 2025(252)：116515.DOI： 10.1016/j.jpba.2024.116515.
|
| [44] |
Lv L， Cui EH， Wang B，et al.Multiomics reveal human umbilical cord mesenchymal stem cells improving acute lung injury via the lung-gut axis[J]． World J Stem Cells， 2023， 15(9)：908-930.DOI： 10.4252/wjsc.v15.i9.908.
|
| [45] |
Wang G， Ma X， Huang W，et al.Macrophage biomimetic nanoparticle-targeted functional extracellular vesicle micro-RNAs revealed via multiomics analysis alleviate sepsis-induced acute lung injury[J]． J Nanobiotechnology， 2024， 22(1)：362.DOI： 10.1186/s12951-024-02597-z.
|
| [46] |
Nie H， Liu H， Shi Y，et al.Combined multi-omics analysis reveals oil mist particulate matter-induced lung injury in rats：pathological damage，proteomics，metabolic disturbances，and lung dysbiosis[J]． Ecotoxicol Environ Saf， 2022(241)：113759.DOI： 10.1016/j.ecoenv.2022.113759.
|
| [47] |
Lu F, Huang T, Chen R, et al. Multi-omics analysis reveals the interplay between pulmonary microbiome and host in immunocompromised patients with sepsis-induced acute lung injury[J]． Microbiol Spectr， 2024， 12(12)：e0142424.DOI： 10.1128/spectrum.01424-24.
|