Diagnostic accuracy of the second generation dual-source dual-energy CT myocardial perfusion imaging in patients with suspicious myocardial infarction

doi:10.3877/cma.j.issn.2095-655X.2015.03.005

Abstract

Abstract:

Objectives

To evaluate the diagnostic accuracy of the second generation dual-source dual-energy CT myocardial perfusion imaging in patients with suspicious myocardial infarction.

Methods

Fifty-six patients underwent dual-source dual-energy myocardial perfusion imaging, of which forty patients had follow-up results [confirmed by catheter coronary angiography, cardiac troponin I elevation and Electrocardiogram (ECG) changes and evolution of acute myocardial infarction] within 30 days.Catheter coronary angiography and clinical data served as the standard of references.The sensitivity, specificity and positive and negative predictive values of the second generation dual-source dual-energy CT myocardial perfusion in the detection of myocardial infarction were evaluated.The coronary image quality and radiation dose were evaluated.

Results

Diagnostic accuracy: the sensitivity, specificity and positive and negative predictive values were 95.0%, 97.0%, 86.4% and 98.9%, respectively.Coronary image quality: one patient with non-diagnostic images was due to motion artifacts occurred at the right coronary artery and left circumflex artery; another patient′s vessels were unassessable due to the motion artifacts induced by high heart rate variability; the other patients′ image quality were good.Radiation dose: the average effective radiation dose was (6.1±1.5)mSv.

Conclusion

One-step dual-source dual-energy CT myocardial perfusion scan combined with coronary CTA provide high diagnostic accuracy for detecting myocardial infarction with lower radiation exposure in patients with suspicious myocardial infarction.

Key words: Tomography, x-ray computed, Myocardial perfusion imaging, Myocardial infarction, Diagnosis

Ruijuan Han, Kai Sun, Kuncheng Li, Ruiping Zhao, Wenhuan Li, Shuancheng Bai, Junyan Wang, Hongyu Li, Yaojun Lu. Diagnostic accuracy of the second generation dual-source dual-energy CT myocardial perfusion imaging in patients with suspicious myocardial infarction[J]. Chinese Journal of Diagnostics(Electronic Edition), 2015, 03(03): 173-178.

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References 28

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