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Chinese Journal of Diagnostics(Electronic Edition) ›› 2018, Vol. 06 ›› Issue (04): 268-271. doi: 10.3877/cma.j.issn.2095-655X.2018.04.012

Special Issue:

• Clinical Study • Previous Articles     Next Articles

Clinical application analysis of traditional Chinese medicine in reducing serum Interleukin-6 level

Jinlong Liu1, Hua Li1, Hengan Chen1, Kaiwen Deng1, Zujian Xu1,()   

  1. 1. Department of Orthopedics, the Hospital of Traditional Chinese Medicine Affiliated to Southwest Medical University, Luzhou 646000, China
  • Received:2018-09-26 Online:2018-11-26 Published:2018-11-26
  • Contact: Zujian Xu
  • About author:
    Corresponding author: Xu Zujian, Email:

Abstract:

Objective

To explore the common Chinese medicine drugs used to reduce the level of serum interleukin-6 (IL-6).

Methods

Retrieving the key words "IL-6" and "tranditional Chinese medicine" from the year 2007 to 2018 in CNKI, CQVIP and Wanfang data bases. The documents that met the standards were selected from the retrieved journal literatures, and the Chinese medicines that qualified the inclusion standards were selected from the literatures and analyzed.

Results

A total of 1 067 journal articles were retrieved (including 183 articles from CNKI, 351 articles from CQVIP and 533 articles from Wanfang), and 485 articles met the inclusion criteria, including 160 Chinese herbal medicines. Finally, 18 kinds of Chinese medicine were incorporated. Among them, there were 7 kinds of heat-clearing medicine, 6 kinds of tonic medicine, 2 kinds of blood-activating and stasis-relieving medicine, 2 kinds of water-staining and osmotic medicine, 2 kinds of relieving exterior disorder medicine, 1 kind of diarrhea medicine, and 1 kind of phlegm medicine. 5/7 of the heat-clearing drugs belonged to the liver, and 5/6 of the tonifying drugs belonged to the spleen. The drug with the highest frequency of occurrence was Astragalus membranaceus.

Conclusions

Heat-clearing medicine and tonifying medicine are commonly used traditional Chinese medicine drugs for reducing the level of serum IL-6. Liver drainage and spleen repair are commonly used in traditional Chinese medicine to reduce serum IL-6 level.

Key words: Interleukin-6, Drugs, Chinese herbal, Heat-clearing medicine, Tonify deficiency medicine

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