To explore the clinical diagnosis characteristics, the safety and feasibility of stenting thrombectomy technique in patients with wake-up stroke.

Clinical data of three patients with wake-up stroke who underwent stent thrombectomy in the Department of Neurology, Changzhi People′s Hospital from October 2017 to April 2018 were collected. Clinical features of patients and their vascular reperfusion, complications and neurologic improvement after stent thrombectomy were analyzed and the functional scores of the modified Rankin scale (mRS) and Barther index (BI) after 90 days of operation were evaluated.

Of the 3 cases, 2 patients were cardiogenic infarction, 1 was atherosclerotic infarction, and all had conscious disorder. NIHSS scores were 13-25, all of them were anterior circulation large vessel occlusion. The occluded vessels were successfully recanalized and cerebral infarction thrombolysis grading system (TICI) score≥2b. There were no intracranial hemorrhage by the brain CT reexamination after operation, and with no significant expansion of cerebral infarction at the same time. 30 days after operation, the NIHSS scores (10-20 points) were lower than those at admission. The postoperative mRS score was 3 points in 1 case and 2 points in the other 2 cases and the BI score was 80 points in 1 case and 95 points in the other 2 cases after 90 days of operation.

Stent thrombectomy has a high vascular recanalization rate in patients with wake-up stroke, and can significantly improve the clinical prognosis of patients.