To investigate the diagnostic characteristics of facial abscess caused by Streptococcus constellatus.

The clinical data of a case of facial abscess caused by Streptococcus constellatus admitted to the Oncology Department of Tianmen First People′s Hospital on June 27, 2020 were retrospectively analyzed, and the relevant literatures were reviewed.

The patient presented with a mass in the right maxillofacial region, with partial skin ulceration and purulent discharge. The patient had an anamnesis of nasopharyngeal carcinoma. Imaging indicated right middle ear mastoiditis and sinusitis. Laboratory examination found that IgA antibody of human herpesvirus was weakly positive, C-reactive protein level was 11.07 mg/L, procalcitonin level was 1.26 μg/L, blood culture was negative, and Streptococcus constellatus was detected in wound secretion. The pathogen was resistant to erythromycin and clindamycin.

As a kind of opportunistic pathogen, Streptococcus constellatus can cause suppurative infection in various tissues and organs of human body, which should arouse clinical attention. We should improve the detection rate of pathogenic bacteria, so as to achieve early diagnosis and treatment.