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Chinese Journal of Diagnostics(Electronic Edition) ›› 2023, Vol. 11 ›› Issue (02): 125-127. doi: 10.3877/cma.j.issn.2095-655X.2023.02.011

• Diagnosis and Treatment of Endocrine Metabolic Diseases • Previous Articles     Next Articles

Research progress of selenium combined with different drugs in the treatment of Hashimoto thyroiditis

Zhengyu Wang1, Lin Sun2,()   

  1. 1. College of Clinical Medicine, Jining Medical University, Jining 272013, China
    2. Department of Endocrinology, the First People′s Hospital of Jining, Jining 272002, China
  • Received:2022-01-29 Online:2023-05-04 Published:2023-05-05
  • Contact: Lin Sun

Abstract:

Selenium is a trace mineral that is essential for maintaining human health. Selenium is present in the body as selenoproteins, which are involved in antioxidant, anti-inflammatory process, and the production of active thyroid hormone synthesis. The imbalance of oxidative stress and the downregulation of immune function that results from a lack of selenoproteins in the body may contribute to the occurrence and progression of Hashimoto thyroiditis (HT). Selenium supplementation may aid in the prevention and treatment of HT. The study of the relationship between selenium insufficiency and HT, as well as the prevention and treatment of selenium deficiency, has begun to attract domestic and international attention. This article discusses recent developments in selenium and its use in combination with other drugs for the prevention and treatment of HT.

Key words: Selenium, Hashimoto thyroiditis, Vitamin D, Thyroxine, Inositol

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