Research progress of autophagy regulating cell ferroptosis and the effects of ferroptosis in tumors

doi:10.3877/cma.j.issn.2095-655X.2023.02.015

Abstract

Abstract:

Ferroptosis is a new type of cell death related to iron overload and lipid peroxidation, which is different from traditional apoptosis and occurs during tumor development. Autophagy is a degradation and circulatory system that is essential for removing waste from cells. According to researches, autophagy may disrupt intracellular homeostasis and lead to ferroptosis, which has been linked to tumor development. In order to provide new ideas for tumor treatment, this article summarizes the mechanism of autophagy regulating ferroptosis and briefly introduces the role of autophagy and ferroptosis in different tumors.

Key words: Ferroptosis, Autophagy, Regulate, Tumor, Treatment

Minchang Li, Changlin Ma. Research progress of autophagy regulating cell ferroptosis and the effects of ferroptosis in tumors[J]. Chinese Journal of Diagnostics(Electronic Edition), 2023, 11(02): 140-144.

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