Abstract:
Objective
To explore the diagnostic efficacy of diffusion weighted imaging （DWI） and high resolution CT （HRCT） in differentiating benign and malignant pulmonary lesions.
Methods
From July 2014 to February 2015，a retrospective analysis was conducted on 114 patients with pulmonary lesions who were treated in the Department of Thoracic Surgery of the First Affiliated Hospital of Guangzhou Medical University.All patients underwent chest HRCT scanning and MR-DWI examination.Based on the initial HRCT report results，the pulmonary lesions were divided into HRCT definitive diagnosis group and indistinguishable group.The postoperative pathological results were used as the "gold standard"，and the diagnostic efficacy was evaluated using the receiver operating characteristic （ROC） curve.
Results
Among the 114 patients，97 cases （85.09%，97/114） were in the definitive diagnosis group，the areas under the ROC curve （AUC） of DWI and HRCT were 0.832 （95%CI：0.742-0.900） and 0.869 （95%CI：0.785-0.969），respectively，and the difference was not statistically significant （Z=0.511，P=0.609）.There were 17 cases （14.91%，17/114） in the indistinguishable group，with AUCs of 0.829 （95%CI：0.571-0.964） and 0.500（95%CI：0.254-0.746），respectively，and the difference was statistically significant（Z=3.077，P=0.002）.
Conclusions
DWI and HRCT have comparable diagnostic efficacy.In pulmonary lesions that are difficult to distinguish by HRCT，DWI can provide additional diagnostic value.
Key words:
Pulmonary lesions,
Diffusion weighted imaging,
High resolution CT,
Diagnosis，differential,
Diagnostic performance
Dongcheng Li, Tao Chen, Xinchun Li, Jiaxuan Zhou, Yingying Bao, Jiaxi Yu, Qi Wan. Comparative diagnostic efficacy of magnetic resonance diffusion weighted imaging and HRCT in differentiating benign and malignant pulmonary lesions[J]. Chinese Journal of Diagnostics(Electronic Edition), 2024, 12(04): 249-253.