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Chinese Journal of Diagnostics(Electronic Edition) ›› 2025, Vol. 13 ›› Issue (01): 32-37. doi: 10.3877/cma.j.issn.2095-655X.2025.01.005

• Diagnosis and Treatment of Obstetrics and Gynecology Diseases • Previous Articles     Next Articles

Diagnostic features and literature review of giant multilocular cystic leiomyoma of the uterus

Xiru Zhang1, Yingxue Yuan1, Zhixin Cao1,()   

  1. 1. Department of Pathology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China
  • Received:2024-12-15 Online:2025-02-26 Published:2025-03-11
  • Contact: Zhixin Cao

Abstract:

Objective

To investigate the diagnostic features of giant multilocular cystic leiomyoma of uterus.

Methods

The clinical data of a newly diagnosed patient with a giant pelvic cavity mass admitted to the Gynecology Department of Shandong Provincial Hospital on August 5, 2023 were collected, and the literature was reviewed to summarize the diagnostic features of giant multilocular cystic leiomyoma.

Results

The patient, a 36-year-old female, had experienced abdominal enlargement for more than 2 years,with worsening symptoms over the past 2 months, accompanied by frequent urination, ascites, and weight gain. Ultrasound examination revealed a large cystic-solid mass in the abdominal pelvic cavity, initially suspected as an ovarian malignancy, and a cystic mass in the right adnexal area, suspected to be a teratoma,and subserous myoma of the uterus. Enhanced CT of the pelvis and abdomen initially suggested ovarian cystadenocarcinoma. The pathological diagnosis was giant multilocular cystic leiomyoma in the pelvic cavity,with a maximum transverse diameter of 49.2 cm, complicated with mature cystic teratoma of the ovary and leiomyoma of the uterus. The patient was followed up for 17 months after resection without recurrence.

Conclusion

Giant multilocular cystic leiomyoma, characterized by rare cystic changes and large size, is difficult to diagnose by imaging examination and needs to be confirmed by histopathology and immunohistochemistry.

Key words: Leiomyoma, Uterus, Giant, Cystic degeneration

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