A case of Loffler′s endocarditis diagnosed by echocardiography

doi:10.3877/cma.j.issn.2095-655X.2025.04.009

Abstract

Abstract:

Objective

To explore the echocardiographic features of Loffler′s endocarditis.

Methods

A retrospective analysis was conducted on the clinical data, laboratory tests, ultrasound examinations and diagnosis and treatment course of a patient with Loffler′s endocarditis admitted to the Department of Cardiology of Air Force Medical Center on October 18, 2023. The echocardiographic features were summarized in combination with the literature.

Results

The patient was a 25-year-old male, who suffered cardiac involvement due to severe eosinophilia. Echocardiography showed significant thickening of the endocardium and reduced ventricular heart cavity size. Myocardial contrast echocardiography showed visible blood flow distribution within the thickened endocardium. Enhanced magnetic resonance imaging of the heart indicated an enlarged right atrium, thickened endocardium of the right ventricle with extensive delayed enhancement. After myocardial biopsy, Loffler′s endocarditis was diagnosed. The patient responded well after immunosuppressive therapy. Ultrasound showed that the degree of endocardial thickening gradually decreased and improved.

Conclusion

Echocardiography serves as the preferred imaging method for the clinical diagnosis and for evaluating the therapeutic efficacy in patients with Loffler′s endocarditis.

Key words: Loffler′s endocarditis, Hypereosinophilic syndrome, Echocardiography, Myocardial contrast echocardiography

Huijuan Li, Yahui Sun, Sibo Yang, Yunheng An, Shuping Liu, Li Li. A case of Loffler′s endocarditis diagnosed by echocardiography[J]. Chinese Journal of Diagnostics(Electronic Edition), 2025, 13(04): 266-269.

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