The rapid growth and easy availability of information doesn′t bring good medical service.Physicians′ clinical thinking remain the cornerstone of medical quality.Clinical thinking includes a series of cognitive behaviors such as investigation, analysis, integration, judgment, and inference so as to unveil the essence of diseases.The thinking capability can be achieved by no means other than medical practice itself, which is comprised of collecting data relevant to the problem of interest, evaluating the value of diagnostic clues, formulating diagnostic hypotheses, obtaining more information to accept or exclude the diagnostic hypothesis, assessing causal relationship, dealing with the inherent uncertainties in medicine.To build a successful medical career, young physicians need to improve the ability to think clearly, rigorously, and efficiently.