Abstract:
Objective To investigate the clinical significance of platelet parameters in the diagnose the treatment of children with severe mycoplasma pneumonia (SMPP).
Methods One hundred and eighty patients with mycoplasma pneumonia (MPP) admitted to pediatric department of the Affiliated Hospital of Qingdao University from September 2015 to February 2017 were selcected for a retrospective study.Among them, 90 cases in severe group (SMPP group) and 90 cases in mild group (MPP group), and 90 cases with inguinal hernia as a control group during the same period.The acute period and the recovery period were divided according to the onset time, symptoms, signs and imaging performance peripheral venous blood samples of the three groups were collected to measure platelet parameters separately, including platelet count (PLT), platelet distribution width (PDW), mean platelet volume (MPV), platelet hematocrit (PCT) and platelet-large cell ratio (P-LCR). The t-test and F-test were used to compare the differences between groups.
Results The various parameters of platelet were statistically significant in acute and recovery phase in SMPP group [ PLT(242.06±62.44)×109/L, PDW(10.74±2.34)%, MPV(9.58±0.85)fL, PCT(0.25±0.09)%, P-LCR(22.21±5.98)% and PLT(405.11±101.00)×109/L, PDW (9.87±1.67)%, MPV (9.22±0.67)fL, PCT (0.37±0.09)%, P-LCR (20.07±3.23)%; t=-13.02, 2.87, 3.14, -8.65, 2.30; P<0.05 for each]. Compared with the control group in acute phase, the levels of PLT and PCT in SMPP group were significantly decreased, and in MPP group were significantly increased, the differences were statistically significant [ the statistics of SMPP group, MPP group and control group were PLT(242.06±62.44)×109/L, (333.28±92.60)×109/L, (287.36±36.29)×109/L and PCT(0.25±0.09)%, (0.32±0.12)%, (0.28±0.05)%; F=40.67, 18.52; P<0.05 for each]. Compared with the control group in recovery phase, the levels of PLT and PCT in SMPP and MPP group were significantly increased, the differences were statistically significant [the statistics of SMPP group, MPP group and control group were PLT(405.11±101.00)×109/L、(328.78±76.30)×109/L、(287.36±36.29)×109/L and PCT(0.37±0.09)%, (0.32±0.07)%, (0.28±0.05)%, F=55.56, 39.76; P<0.05 for each].
Conclusion Paying attention to changes in platelet parameters, especially PLT and PCT, is helpful for the diagnose of SMPP early and judgement of the condition changes.
Key words:
Pneumonia, mycoplasma,
Children,
Blood platelets
Xue Yang, Rongjun Lin, Rong Jin, Ling Lu, Renzheng Guan, Xianjin Wang. Clinical significance of platelet parameters in children with severe mycoplasma pneumonia[J]. Chinese Journal of Diagnostics(Electronic Edition), 2018, 06(01): 37-40.