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Chinese Journal of Diagnostics(Electronic Edition) ›› 2019, Vol. 07 ›› Issue (01): 63-65. doi: 10.3877/cma.j.issn.2095-655X.2019.01.013

Special Issue:

• Review • Previous Articles     Next Articles

Progress of proteomics in the diagnosis of Parkinson′s disease

Kaiyang Fan1, Qiang Sun2, Yu Zhang3, Lili Lu4, Jiaxin Song4, Zhaojing Wang4, Li Ma4,()   

  1. 1. Medical Service, the Affiliated Hospital of Jining Medical University, Jining 272029, China
    3. Dalian Center for Disease Control and Prevention, Dalian 116021, China
    4. Department of Epidemiology, Dalian Medical University, Dalian 116044, China
  • Received:2018-02-26 Online:2019-02-26 Published:2019-02-26
  • Contact: Li Ma
  • About author:
    Corresponding author: Ma Li, Email:

Abstract:

Parkinson′s disease is the second most common neurodegenerative disease in humans. The pathogenesis of Parkinson′s disease is currently unclear. Using proteomics approach to study the disease can help us to have a deeper understanding of the disease, and it is of great significance to explore its pathogenesis, to find reliable related biomarkers, and to develop new treatments. The author introduces the application of proteomics in the study of Parkinson′s disease from two aspects. On the one hand, the proteins is studies by acquiring the brain tissue and cerebrospinal fluid of the patients. On the other hand, the desired tissue is obtained for protein tissue research by making animal models of Parkinson′s disease.

Key words: Parkinson disease, Proteomics, Brain, Cerebrospinal fluid, Models, animal

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