Research progress on diagnostic biomarkers of esophageal squamous intraepithelial neoplasia and status of non-endoscopic treatment

doi:10.3877/cma.j.issn.2095-655X.2024.04.013

Abstract

Abstract:

Esophageal cancer is one of the most common malignant tumors of the digestive system，and esophageal squamous intraepithelial neoplasia （ESIN） is widely recognized as a precancerous lesion of esophageal squamous cell carcinoma.Consequently，the diagnosis and treatment of these precancerous conditions are pivotal in the prevention of esophageal cancer.At present，endoscopic examination and treatment are the main means to detect，diagnose and treat ESIN.However，to date，specific biomarkers have not been widely promoted for clinical application，and there is a lack of effective medication for the treatment of ESIN.In recent years，research on the above issues has been continuously carried out and advanced，and some biomarkers and non-endoscopic treatment methods have shown potential value in the diagnosis and treatment of ESIN.The purpose of this paper is to comprehensively review and summarize these research advancements，with the aim of providing valuable references for the early prevention and treatment of esophageal cancer.

Key words: Esophageal squamous intraepithelial neoplasia, Biomarkers, Esophageal neoplasms, Life style, Drug therapy

Ruifang Hu, Lijuan Fan. Research progress on diagnostic biomarkers of esophageal squamous intraepithelial neoplasia and status of non-endoscopic treatment[J]. Chinese Journal of Diagnostics(Electronic Edition), 2024, 12(04): 281-286.

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