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中华诊断学电子杂志 ›› 2022, Vol. 10 ›› Issue (02) : 132 -136. doi: 10.3877/cma.j.issn.2095-655X.2022.02.013

病例诊断思维

Keegan型颈椎病的临床诊断学特征
郑超1, 刘俊朋1, 杜俊杰1, 马炜1, 陈渲宇2, 伍骥1,()   
  1. 1. 100142 北京,空军军医大学空军特色医学中心骨科
    2. 100173 北京,首都医科大学电力教学医院骨科
  • 收稿日期:2021-03-03 出版日期:2022-04-26
  • 通信作者: 伍骥
  • 基金资助:
    军队医学创新工程重点项目(18CXZ018)

Clinical diagnostic features of Keegan′s disease

Chao Zheng1, Junpeng Liu1, Junjie Du1, Wei Ma1, Xuanyu Chen2, Ji Wu1,()   

  1. 1. Department of Orthopedics, Air Force Medical Center, Air Force Medical University, Beijing 100142, China
    2. Department of Orthopedics, Capital Medical University Electric Teaching Hospital, Beijing 100173, China
  • Received:2021-03-03 Published:2022-04-26
  • Corresponding author: Ji Wu
引用本文:

郑超, 刘俊朋, 杜俊杰, 马炜, 陈渲宇, 伍骥. Keegan型颈椎病的临床诊断学特征[J]. 中华诊断学电子杂志, 2022, 10(02): 132-136.

Chao Zheng, Junpeng Liu, Junjie Du, Wei Ma, Xuanyu Chen, Ji Wu. Clinical diagnostic features of Keegan′s disease[J]. Chinese Journal of Diagnostics(Electronic Edition), 2022, 10(02): 132-136.

目的

探讨Keegan型颈椎病的临床诊断学特征及误诊原因。

方法

收集2018年3月至2020年12月空军军医大学空军特色医学中心骨科收治的3例Keegan型颈椎病患者的临床资料,对其诊断、鉴别诊断及转归进行分析,并文献复习。

结果

3例患者中男性1例,女性2例,年龄分别为36岁、36岁、47岁。均无明显诱因出现右肩部外展活动受限,右上臂上举时外侧酸痛;查体右上肢三角肌、肱二头肌肌力明显降低,不伴有感觉异常和脊髓受损的症状和体征。颈椎MRI T2加权像显示相应神经根运动前支明显受压,呈现典型的选择性异常信号特征;脊髓电生理有明确的三角肌、肱二头肌神经性损害的表现;符合Keegan型颈椎病的临床特征。3例患者采取非手术治疗后,均在起病2~3周后开始好转,起病后11~13周痊愈。

结论

肩部外展运动功能障碍而无感觉异常是Keegan型颈椎病典型的临床特征。

Objective

To explore the clinical diagnostic features and the causes of misdiagnosis of Keegan′s disease.

Methods

3 patients with Keegan's disease treated in Orthopedics Department of Air Force Medical Center Affiliated to Air Force Medical University from March 2018 to December 2020 were selected. Their diagnosis, differential diagnosis and outcomes were analyzed, and the relevant literatures were reviewed.

Results

There were 3 patients, 1 male and 2 females, aged 36, 36 and 47 years old, respectively. All the patients had restricted abduction of the right shoulder without obvious inducement, and lateral soreness when lifting the right upper arm. The muscle strength of deltoid muscle and biceps brachii of the right upper limb was significantly reduced, with no symptoms and signs of spinal cord damage and paresthesia. There were typical selective "high spots" in MRI T2WI, and clear neurological damage of the deltoid and biceps in electrophysiology, in line with all the clinical features of Keegan′s disease. With conservation treatment, all patients began to get better 2 to 3 weeks and recovered 11 to 13 weeks after onset.

Conclusion

Shoulder abductor dysfunction without paresthesia is a typical clinical feature of Keegan′s disease.

图1 Keegan型颈椎病患者初诊时体格检查图像注:a图示病例1患者初诊时右肩外展受限,耸肩(箭头所示),三角肌轻度萎缩;b图示病例2患者初诊时右肩外展受限,耸肩(箭头所示),三角肌无萎缩;c图示病例3患者初诊时右肩外展30°受限,上举障碍,耸肩(箭头所示),三角肌无萎缩
表1 3例Keegan型颈椎病患者初诊时主要临床表现及体格检查
序号 年龄(岁) 性别 部位 临床主要症状 主要体格检查
1 36 右肩部 右肩主动外展障碍伴轻度的疼痛7 d,夜间痛不明显。无饮水呛咳及吞咽困难,二便正常,其余肢体及面部无不适 右侧三角肌轻度萎缩,肌力2级;肱二头肌无萎缩,肌力3级;肱三头肌、肩胛下肌、前臂肌群、手内在肌肌力5级;右上肢深、浅感觉无障碍;抬离试验(-),压腹试验(-),肱二头肌腱抗阻试验(-);肱二头肌腱反射减弱,双侧霍夫曼征(-);颅神经及下肢神经系统检查无异常
2 36 右肩部 无诱因出现右肩部外展活动无力6 d,前方上举困难,偶有夜间痛。无饮水呛咳及吞咽困难,二便正常,其余肢体及面部无不适 右侧三角肌无萎缩,肌力2级;肱二头肌无萎缩,肌力3级;肱三头肌、肩胛下肌、前臂肌群、手内在肌肌力均为5级;深、浅感觉无障碍;抬离试验(-)、压腹试验(-),肱二头肌腱抗阻试验(+);肱二头肌腱反射减弱,双侧霍夫曼征(-);颅神经及下肢神经系统检查无异常
3 47 右肩部 7 d前晨起后感右肩部外展受限,上举活动无力,梳头困难,逐渐加重,无肩部夜间痛。无饮水呛咳及吞咽困难,二便正常,其余肢体及面部无不适 右侧三角肌无萎缩,肌力2级;肱二头肌无萎缩,肌力2级;肱三头肌、肩胛下肌、前臂肌群、手内在肌肌力均为5级;抬离试验(+)、压腹试验(-),肱二头肌腱抗阻试验(+),燕尾征(+);深、浅感觉无障碍,肱二头肌腱反射减弱,双侧霍夫曼征(-);颅神经及下肢神经系统检查无异常
图2 Keegan型颈椎病患者初诊时颈椎MRI检查图像注:a、b图为病例2患者颈椎MRI T2加权像,a图示矢状位C4-5椎间盘突出,相应平面硬膜囊受压(箭头所示);b图示轴位C4-5节段椎间盘右侧突出,腹侧运动根受压,呈现异常信号(hight spot)(箭头所示)
图3 Keegan型颈椎病患者治疗5周时体格检查图像注:病例3患者身体略前倾,双上肢主动后伸,右上肢低于健侧,提示右侧三角肌后束肌力减弱,呈"燕尾征"阳性(箭头所示)
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