Clinicopathologic study of serous borderline tumour with microinvasion in ovary

doi:10.3877/cma.j.issn.2095-655X.2016.02.012

Abstract

Abstract:

Objective

To explore the clinicopathological features of serous borderline tumour with microinvasion(SBTM) in ovary.

Methods

The clinical and pathologic findings of 10 patients with SBTM were evaluated.Hematoxylin and eosinstain, immunohistochemistry and histochemistry were performed on the archival paraffin sections.

Results

Among the 10 patients, their age at the time of operation ranged from 22 to 68 years old.The epithelial cells showed mild to moderate atypical hyperplasia, and papillary(8 cases) or micropapillary(2 cases) formation.Individual cells or more cell clusters appeared in tumor stroma, and cytoplasm was eosinophilic.The tumor cells of 10 cases were all diffusely positive for CK7 and CAM5.2 with locally positive for CA125 and WT1.

Conclusions

SBTM is a kind of low-grade malignant tumor, which is easy to be missed when the micro-invasive lesions is small.Due to possible recurrence, long-term follow-up is recommended.

Key words: Serous borderline tumour with microinvasion, Ovary, Disease attributes, Diagnosis

Daosheng Li, Yuanyuan Ban. Clinicopathologic study of serous borderline tumour with microinvasion in ovary[J]. Chinese Journal of Diagnostics(Electronic Edition), 2016, 04(02): 116-119.

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URL: https://zhzdxdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-655X.2016.02.012

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Figures/Tables 8

References 8

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编号	年龄(岁)	临床症状	肿瘤类型	腹膜种植	淋巴结受累	随访情况
1	32	腹部膨隆	经典型	无	无	术后7年健在
2	40	无症状，查体发现	经典型	无	无	术后5年健在
3	55	下腹部疼痛不适	经典型	无	无	术后1年健在
4	42	查体发现盆腔包块	经典型	无	无	术后2年健在
5	48	查体发现附件区囊肿	经典型	无	无	术后3年健在
6	60	腹部增大，不适	经典型	无	无	术后2年健在
7	68	下腹部不适，坠胀感	经典型	无	无	术后7年健在
8	41	查体发现盆腔包块	微乳头型	无	无	术后2年健在
9	33	查体发现卵巢肿物	经典型	无	无	术后1年健在
10	22	下腹部坠胀感	微乳头型	无	无	术后1年复发

编号	年龄(岁)	临床症状	肿瘤类型	腹膜种植	淋巴结受累	随访情况
1	32	腹部膨隆	经典型	无	无	术后7年健在
2	40	无症状，查体发现	经典型	无	无	术后5年健在
3	55	下腹部疼痛不适	经典型	无	无	术后1年健在
4	42	查体发现盆腔包块	经典型	无	无	术后2年健在
5	48	查体发现附件区囊肿	经典型	无	无	术后3年健在
6	60	腹部增大，不适	经典型	无	无	术后2年健在
7	68	下腹部不适，坠胀感	经典型	无	无	术后7年健在
8	41	查体发现盆腔包块	微乳头型	无	无	术后2年健在
9	33	查体发现卵巢肿物	经典型	无	无	术后1年健在
10	22	下腹部坠胀感	微乳头型	无	无	术后1年复发

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