Comparison of clinical features of patients with irritable bowel syndrome before and after flupentixol and melitracen treatment

doi:10.3877/cma.j.issn.2095-655X.2016.03.004

Abstract

Abstract:

Objective

To observe the effect of the Deanxit combined with bifidobacteria in the patients with irritable bowel syndrome(IBS).

Methods

Sixty-eight cases of IBS patients from the Affiliated Hospital of North China University of Science and Technology were enrolled from January to December in 2015.In accordance with the principle of parallel group design, 68 cases of IBS patients were divided into treated group (34 cases) and controlled group (34 cases). Conventional therapy combined with bifidobacteria was given only in controlled group, and conventional therapy combined with bifidobacteria and Deanxit was given in treated group.After 4 weeks of treatment, the clinical symptoms of 2 groups of patients with abdominal pain, abdominal discomfort, diarrhea, constipation, anxiety and other clinical symptoms were observed, and the therapeutic effect was compared.

Results

Compared with the control group, the treatment group had significant differences in abdominal pain (30 cases of treatment group, 28 cases of control group, χ²=6.91, P=0.03), abdominal discomfort(32 cases of treatment group, 31 cases of control group, χ²=7.03, P=0.02), diarrhea(31 cases of treatment group, 32 cases of control group, χ²=8.76, P=0.01), constipation(26 cases of treatment group, 27 cases of control group, χ²=7.35, P=0.02) and anxiety(29 cases of treatment group, 30 cases of control group, χ²=16.70, P=0.01).

Conclusion

Deanxit combined with bifidobacteria in the treatment of irritable bowel syndrome has good curative effect and can improve clinical symptoms.

Key words: Irritable bowel syndrome, Flupentixol and melitracen, Bifidobacteria

Guoshun Zhang, Bin Liu, Zhengya Fang, Dongmei Meng, Zhiting Li, Xiujing Zhang, Ning Ma, Xuejun Zhang. Comparison of clinical features of patients with irritable bowel syndrome before and after flupentixol and melitracen treatment[J]. Chinese Journal of Diagnostics(Electronic Edition), 2016, 04(03): 157-159.

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