The role of circulating microRNAs in the pathogenesis and intestinal inflammatory activity of ulcerative colitis

doi:10.3877/cma.j.issn.2095-655X.2017.04.001

Abstract

Abstract:

Ulcerative colitis is the main type of inflammatory bowel diseases with an increasing incidence by years.The pathogenesis is complex, its diagnosis and evaluation depend on colonoscopy.In recent years, microRNAs have been proved to be participating in regulating target mRNAs which modify gene expression, regulate cell differentiation, apoptosis and inflammation.Tissue and circulating microRNAs are found to be related to the pathogenesis and inflammatory activity of ulcerative colitis.MicroRNAs are promising biomarker in ulcerative colitis.

Key words: Colitis, ulcerative, MicroRNAs, Biological markers

Jixi Liu. The role of circulating microRNAs in the pathogenesis and intestinal inflammatory activity of ulcerative colitis[J]. Chinese Journal of Diagnostics(Electronic Edition), 2017, 05(04): 217-220.

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