Traumatic coagulation abnormalities and trauma induced coagulopathy in high altitude environment

doi:10.3877/cma.j.issn.2095-655X.2020.03.005

Abstract

Abstract:

High altitude region is an important strategic area for national defense and economic construction in our country. Trauma caused by various reasons in high altitude region occurs from time to time. Traumatic coagulopathy and trauma induced coagulopathy are important factors that threaten the health of the wounded. Recent relevant researches reveal that the special geographical environment of the plateau region can affect the coagulation function of normal migrants from the plain, and appear the state of hypercoagulability and fibrinolysis. Post-traumatic coagulation abnormalities in plateau regions are also mainly manifested as difficult to correct the hypercoagulability. According to previous studies, the author puts forward the possible related characteristics of traumatic coagulopathy in plateau regions, and provides important reference for the follow-up guidance of the diagnosis and treatment of traumatic coagulation abnormalities and trauma induced coagulopathy in peacetime and wartime.

Key words: High altitude, Wounds and injuries, Coagulation function, Trauma induced coagulopathy

Dongfeng Zeng, Jin Wang. Traumatic coagulation abnormalities and trauma induced coagulopathy in high altitude environment[J]. Chinese Journal of Diagnostics(Electronic Edition), 2020, 08(03): 168-170.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhzdxdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-655X.2020.03.005

https://zhzdxdzzz.cma-cmc.com.cn/EN/Y2020/V08/I03/168

References 23

[1]	Petros S．Trauma-induced coagulopathy[J]．Hämostaseologie，2019，39(1): 20-27.
[2]	Kushimoto S, Kudo D, Kawazoe Y．Acute traumatic coagulopathy and trauma-induced coagulopathy：an overview[J]．J Crit Care，2017，27(4): 399-407.
[3]	程海花，阿祥仁，王立萍．不同海拔地区健康人群血管内皮细胞功能指标的变化[J]．检验医学，2010，25(8): 647-648. URL
[4]	公保才旦．从玉树地震创伤救治经验谈高原创伤特点与救治[J]．临床误诊误治，2015，28(7): 61-63.
[5]	崔建华，张西州，谢印芝，等．平原人进驻高原后凝血和纤溶功能的改变及其意义[J]．中国应用生理学杂志，2001，17(4): 363-365.
[6]	李丽娟，王超，朱敏．健康青年急进高原后凝血纤溶系统改变的研究[J]．西南国防医药，2007，17(5): 571-572.
[7]	雷应权，冯国君，越涛，等．高原汉族军人凝血纤溶系统的研究[J]．西藏医药杂志，2003，24(3): 9-10.
[8]	崔建华，张西州，朱国斌，等．海拔4300 m世居藏族和移居汉族青年凝血及纤溶功能对比观察[J]．西藏医药杂志，2000，21(4): 3-5，73.
[9]	严军，余静，李森，等．特殊环境战创伤感染防治策略[J/CD]．中华诊断学电子杂志，2020，8(2): 100-102.
[10]	李琳业，侯明．高原创伤的特点及其救治[J]．高原医学杂志，2016，26(3): 61-63.
[11]	车惠民．高原战伤的救治//黎鳌，盛志勇，王正国，等．现代战伤外科学[M]．北京：人民军医出版社，1998：586-596.
[12]	屈纪富，胥全宏，文亮，等．高原地区创伤病人临床特点分析[J]．创伤外科杂志，2012，14(4): 317-319.
[13]	钱惠岗，公保才旦，樊建林，等．高原地区严重创伤后多脏器功能不全患者凝血功能的变化及意义[J]．高原医学杂志，2011，21(3): 1-4.
[14]	张渊，李涛，李建勋，等．高原地区颅脑损伤后凝血功能异常的临床分析[J]．中国临床神经外科杂志，2014，19(3): 150-152.
[15]	Cohen MJ, Christie SA.Coagulopathy of trauma[J]．Crit Care Clin，2017，33(1): 101-118.
[16]	Shaz BH, Winkler AM, James AB，et al.Pathophysiology of early trauma induced coagulopathy：emerging evidence for hemodilution and coagulation factor depletion[J]．J Trauma，2011，70(6): 1401-1407. URL
[17]	杨策，王海燕，杜娟，等．精准医学思维对创伤诊治模式的影响与前景[J/CD]．中华诊断学电子杂志，2015，3(2): 98-101. URL
[18]	岳茂兴，梁华平，都定元．急性创伤性凝血功能障碍与凝血病诊断和卫生应急处理专家共识(2016)[J/CD]．中华卫生应急电子杂志，2016，2(4): 197-203.
[19]	Sumislawski JJ, Christie SA, Kornblith LZ, et al. Discrepancies between conventional and viscoelastic assays in identifying trauma-induced coagulopathy[J]．Am J Surg，2019，217(6): 1037-1041.
[20]	Brenni M, Worn M, Bruesch M，et al.Successful rotational thromboelastometry-guided treatment of traumatic haemorrhage，hyperfibrinolysis and coagulopathy[J]．Acta Anaesthesiol Scand，2010，54(1): 111-117.
[21]	Doran CM, Woolley T, Midwinter MJ.Feasibility of using rotational thromboelastometry to assess coagulation status of combat casualties in a deployed setting[J]．J Trauma，2010，69(Suppl 1): S40-S48.
[22]	Schöchl H, Nienaber U, Hofer G，et al.Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM)-guidedadministration of fibrinogen concentrate and prothrombin complex concentrate[J]．Crit Care，2010，14(2): R55.
[23]	谢玉海，王学军．高原地区患者术前凝血功能特征及血栓弹力图评估凝血功能的价值研究[J]．中国现代医学杂志，2017，27(17): 80-83.

Please choose a citation manager

Content to export