To investigate the relationship between epicardial fat thickness, CT value, the scores of synergy between percutaneous coronary intervention with TAXUSTM and cardiac surgery (Syntax score) and coronary artery disease.

From February 2017 to October 2018, patients in Cardiology Department of Lanling People′s Hospital were selected. A total of 69 patients with coronary artery disease diagnosed by coronary angiography were enrolled in the study group, 60 persons with normal physical examination were selected as the control group.All cases underwent coronary CT angiography (CTA) examination, epicardial fat thickness and CT value were compared between the two groups. To compare the differences in epicardial fat thickness and CT values with different Syntax scores according to coronary angiography between the two groups.

The levels of triglyceride [(1.62±0.68)mmol/L] and total cholesterol [(5.12±1.83)mmol/L] in the study group were significantly higher than those in the control group [(1.50±0.53), (4.90±1.20)mmol/L] (t=4.60, 3.82, all P<0.05). For the levels of high-density lipoprotein and low-density lipoprotein cholesterol, there were no significant differences between the study group [(1.49±0.43)mmol/L, (2.45±0.63)mmol/L] and the control group [(1.50±0.55)mmol/L, (2.50±0.55)mmol/L] (t=0.55, 0.34, all P>0.05). The epicardial fat thickness of the study group [(12.30±2.66)mm] was higher than that of the control group [(9.50±1.85)mm] (t=8.60, P<0.01). The epicardial fat CT value [(-98.60±15.66)HU] in the study group was higher than that in the control group [(-70.55±9.82)HU] (t=19.36, P<0.01). Epicardial fat thickness [(11.30±2.20)mm], epicardial fat CT value [(-90.60±9.55)HU] and the average Syntax score [(-17.32±8.42)point] in patients with low score group were lower than those in the high score group [(14.50±2.76)mm, (-115.30±13.36)HU, (-30.44±9.19) point], the differences were statistically significant (t=6.42, 9.58, 21.15, all P<0.01).

Epicardial fat thickness and CT value may affect the Syntax score of patients with coronary heart disease, which can be used as a reference index for disease evaluation, and it has a promotional value.