Home    中文  
 
  • Search
  • lucene Search
  • Citation
  • Fig/Tab
  • Adv Search
Just Accepted  |  Current Issue  |  Archive  |  Featured Articles  |  Most Read  |  Most Download  |  Most Cited

Chinese Journal of Diagnostics(Electronic Edition) ›› 2024, Vol. 12 ›› Issue (02): 138-142. doi: 10.3877/cma.j.issn.2095-655X.2024.02.014

• Review • Previous Articles    

Research progress on the physiological and pathological effects of apelin/APJ system

Ruihao Wang1, Yunlu Jiang1, Yanjun Tian2,()   

  1. 1. School of Mental Health, Jining Medical University, Jining 272067, China
    2. Medical Laboratory, Jining Medical University, Jining 272067, China
  • Received:2024-01-17 Online:2024-05-26 Published:2024-06-05
  • Contact: Yanjun Tian

Abstract:

Apelin is a multifunctional bioactive peptide that exerts corresponding biological effects by binding to its receptor APJ. The apelin/APJ system, as an important regulator of the body, is widely involved in physiological and pathological processes of the cardiovascular system, metabolic system, nervous system, and other aspects. An increasing number of studies indicate that the apelin/APJ system can serve as a key target for prevention and control, and prognosis of clinical diseases. This article provides a review of the physiological and pathological effects of the apelin/APJ system and explores the specific mechanisms and the prospects for its clinical applications, in order to promote the development of new drugs and look for new treatment strategies.

Key words: Apelin, APJ, Physiological and pathological effects, Diseases, Clinical applications

京ICP 备07035254号-20
Copyright © Chinese Journal of Diagnostics(Electronic Edition), All Rights Reserved.
Tel: 0537-3616261 E-mail: zhzdxzz@126.com
Powered by Beijing Magtech Co. Ltd