In the early 1960s, the traditional concept of disease and the dichotomy of function/organ within biological medical model were criticized by Engle.However, there is little awareness of the limitation of making organic disease the primary focus of clinical medicine and medical research.It is not that certain disorders lack organic explanations, but our assessment is inadequate in most clinical encounters.Bio-psycho-social medical model has been at theoretical level and been far from clinical practice for lacking of operational strategies or methods.The primary aim of psychosomatic medicine is just the incorporation of its operational strategies with clinical practice.Psychosomatic model will offer unprecedented possibility for the identification and treatment of various difficult medical problems.Taking full advantage of clinimetrics methods may be a good remedy for biological model and improve patient′s clinical course, final outcome and the quality of life.