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Chinese Journal of Diagnostics(Electronic Edition) ›› 2020, Vol. 08 ›› Issue (01): 52-56. doi: 10.3877/cma.j.issn.2095-655X.2020.01.012

Special Issue:

• Clinical Study • Previous Articles     Next Articles

Diagnostic features analysis of rapid eye movement sleep-related bradyarrhythmia syndrome

Lin Lin1, Chan Li1, Jingru Lin2, Rui Xu3,()   

  1. 1. Weifang Medical University, Weifang 261053, China; Department of Cardiology, the First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Jinan 250014, China
    2. Department of Cardiology, Shandong Provincial Third Hospital, Jinan 250031, China
    3. Department of Cardiology, the First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Jinan 250014, China
  • Received:2019-08-19 Online:2020-02-26 Published:2020-02-26
  • Contact: Rui Xu
  • About author:
    Corresponding author: Xu Rui, Email:

Abstract:

Objective

To explore the diagnostic features and treatment of rapid eye movement (REM) sleep-related bradyarrhythmia syndrome.

Methods

The clinical data of the patient with bradyarrhythmia syndrome related to REM sleep admitted to Cardiology Department of Shandong Provincial Qianfoshan Hospital on September 14, 2017 were analyzed retrospectively, and the relevant literatures were reviewed.

Results

The results of 24-hour holter showed sinus tachycardia, sinus arrest (sinus arrest was more than 2.0 s for 525 times, and the longest stop was 3.13 s), first degree, second degree Ⅰ, second degree Ⅱ atrioventricular block and occasional supraventricular premature beat. Sinus tachycardia mainly occured in daytime after movement, sinus arrest and atrioventricular block mainly occured from 24∶00 to 7∶00 am. Heart rate variability showed the standard deviation of RR interval of sinus heart beat was 121 ms, the peak appeared at night, the fastest heart rate was 169 times/min within 24 hours, no ST-T change. No abnormality was found in myocardial enzyme, doppler echocardiography and chest radiograph. After removing the inducement of sympathetic nerve excitation, the patient′s arrhythmia at night was significantly improved.

Conclusion

The hyperactivity of the sympathetic during the day maybe one of the causes of the bradyarrhythmia related to REM sleep.

Key words: Sleep, rapid eye movement, Sinus arrest, cardiac, Autonomic nervous system

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