In the peacetime, various explosions, such as blasting operation, terrible attack and uncontrolled explosions of explosive dangerous goods always account for severe casualty.Through a retrospective analysis in recent ten years, the giant explosive accidents were found to show the tendency of gradual increase in China.Unfortunately, the explosive blast injury remains the principal casualty reasons.It has been attracted much attention in the medical circles.Recently, the main interest in the blast injury focuses on the step-by-step improvement of diagnostic and therapeutic levels.The protective measures on the explosive blast injury have also been investigated actively.Some valuable data have been gathered.However, it remains to be strengthened in the protective materials, protective devices as well as the theoretical evacuation of defensive strategy.In the present paper, we reflected the real need of defensive measures from the view of diagnosis and therapeutics of blast injury.The precision and suitability of protective strategy concerning the non-martial explosions have also been extensively discussed with regard to the current situation of the research in the protective materials as well as equipments of blast injury.Consequently, it is of great importance in theory and practice in the defense of blast injury owing to the long-term existence of explosive accidents in future.