Clinicopathological characteristics of intestinal lymphoid polyposis in adults

doi:10.3877/cma.j.issn.2095-655X.2016.01.015

Abstract

Abstract:

Objective

To explore the clinicopathological characteristics of intestinal lymphoid polyposis in adults.

Methods

The histopathological features and immunophenotype of two cases of adult intestinal lymphoid polyposis were studied, relevant literatures were reviewed.

Results

A total of 1 male and 1 female were studied, aged 65 and 46, respectively.In all two cases, identification of the polyposis was incidental during the examination of resected of terminal ileum and ileocecal region due to other diseases.Gross findings were multiple polyps in the terminal ileum, measuring 0.1 cm~0.5 cm in diameter.Hyperplasia of mucosa-associated lymphoid tissue was noticed microscopically.The polyps were composed of closely aggregated lymphoid follicles.The follicles contained prominent germinal centers surrounded by a mantle of small lymphocytes.Immunohistochemical staining showed the follicles to be composed of CD20(+ ) and Clyclin D1(-) lymphocytes.Cells in germinal center did not express Bcl-2.

Conclusion

Lymphoid polyposis is a rare benign tumor featuring unique clinicopathological characteristics, and the diagnosis relies on histopathological analysis and some ancillary markers.

Key words: Lymphoid polyposis, Pathology, Tumor, Diagnosis

Qinhua Shao, Juan Yang, Fan Zhang, Sheng Zheng. Clinicopathological characteristics of intestinal lymphoid polyposis in adults[J]. Chinese Journal of Diagnostics(Electronic Edition), 2016, 04(01): 52-55.

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Figures/Tables 3

References 16

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